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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
20.61
Human Site:
T593
Identified Species:
34.87
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
T593
E
G
F
L
A
A
L
T
T
A
N
Q
D
G
R
Chimpanzee
Pan troglodytes
XP_520821
925
103112
T593
E
G
F
L
A
A
L
T
T
A
N
Q
D
G
R
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
T574
E
G
F
L
A
A
L
T
T
A
N
Q
D
G
R
Dog
Lupus familis
XP_543872
907
102087
T575
E
S
F
L
A
A
L
T
T
A
N
Q
D
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
L545
I
E
A
F
L
A
A
L
T
T
A
N
Q
D
G
Rat
Rattus norvegicus
XP_001070646
845
94905
R523
D
G
R
V
I
V
N
R
Q
G
S
V
G
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
T605
E
G
F
L
A
A
L
T
T
A
N
Q
D
G
R
Chicken
Gallus gallus
XP_416375
940
105739
G605
S
P
L
M
H
I
E
G
F
L
S
A
L
T
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
F552
P
M
M
L
A
E
S
F
L
F
A
L
T
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
T548
L
A
F
L
E
T
L
T
S
N
A
E
D
G
R
Honey Bee
Apis mellifera
XP_001121183
769
88327
I480
V
R
D
A
R
A
V
I
L
A
G
G
T
M
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
G491
A
R
A
I
I
V
A
G
G
T
M
Q
P
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
E564
S
I
K
Y
M
L
L
E
P
S
K
P
F
E
S
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
E679
K
I
P
P
P
R
G
E
L
Q
D
M
K
L
S
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
100
100
93.3
N.A.
13.3
6.6
N.A.
100
0
N.A.
13.3
N.A.
46.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
13.3
26.6
N.A.
100
13.3
N.A.
13.3
N.A.
60
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
43
50
15
0
0
43
22
8
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
8
0
43
8
0
% D
% Glu:
36
8
0
0
8
8
8
15
0
0
0
8
0
8
8
% E
% Phe:
0
0
43
8
0
0
0
8
8
8
0
0
8
0
0
% F
% Gly:
0
36
0
0
0
0
8
15
8
8
8
8
8
43
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
15
0
8
15
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% K
% Leu:
8
0
8
50
8
8
50
8
22
8
0
8
8
8
0
% L
% Met:
0
8
8
8
8
0
0
0
0
0
8
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
36
8
0
8
8
% N
% Pro:
8
8
8
8
8
0
0
0
8
0
0
8
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
43
8
8
0
% Q
% Arg:
0
15
8
0
8
8
0
8
0
0
0
0
0
0
43
% R
% Ser:
15
8
0
0
0
0
8
0
8
8
15
0
0
0
22
% S
% Thr:
0
0
0
0
0
8
0
43
43
15
0
0
15
8
0
% T
% Val:
8
0
0
8
0
15
8
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _